Ernesto Bernal-Mizrachi, M.D.
- Office: 305-243-5631
- Fax: 305-243-6575
- Endocrinology, Diabetes and Metabolism
- Internal Medicine
Diabetes Type 1 & Type 2, Rare form genetic diabetes
- American Bd of Int Med-Endocrinology Diabetes & Metabolism
- Chief, Division of Endocrinology
- Professor of Medicine
Dr. Bernal-Mizrachi's research over the last 15 years has focused on the regulation of pancreatic beta cell mass and function, with a particular interest in Akt and mTOR signaling pathways in beta cell proliferation. His laboratory has made major contributions to our understanding of signaling pathways that regulate beta cell expansion and survival. The long term goal of these signaling studies is to develop novel pharmacological agents for the treatment and cure of type 1 and 2 diabetes. In addition, his laboratory also explores how the fetal environment can alter the susceptibility to diabetes later in life, a concept that has major implications to human diabetes. Finally, his group has been exploring the importance of glucagon and alpha cells in the regulation of glucose homeostasis with particular interest in discovering avenues to decrease hypoglycemia in diabetes. He has an excellent record of grant funding and currently is principal investigator on RO1 grants from the National Institutes of Health, a VA MERIT award and two foundation grants including American Diabetes Association and Juvenile Diabetes Research Foundation.